ZNRD2

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNRD2 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNRD2-associated genes across cancer lineages are Sebocytes and Osteoblast. Each is linked with ZNRD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNRD2-to-partner and partner-to-ZNRD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sebocytes grouped by ZNRD2-low versus ZNRD2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNRD2→partner) and Y-score (partner→ZNRD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSebocytes →+0.033+3.021.022.01931
UCECOsteoblast →-0.058-2.978.026.03711
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Sebocytes by ZNRD2 expression — UCEC

Box plot of Sebocytes in ZNRD2-low vs ZNRD2-high samples in UCEC.

Explore this box plot interactively →

Exploration