ZNHIT6

Across TCGA patient cohorts, ZNHIT6 mutation is significantly associated with the RNA expression of many other genes, with 1,158 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNHIT6-associated genes across cancer lineages are MTND4LP19, RN7SL817P, and PYY3. Each is linked with ZNHIT6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNHIT6-to-partner and partner-to-ZNHIT6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND4LP19 grouped by ZNHIT6-low versus ZNHIT6-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNHIT6→partner) and Y-score (partner→ZNHIT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MTND4LP19 →	+0.138	+4.704	<.001	.005	3	2
BLCA	RN7SL817P →	+0.125	+4.691	.003	.001	3	2
BLCA	PYY3 →	+0.114	+6.048	<.001	<.001	3	2
UCEC	IGHD3-16 →	+1.148	+2.095	<.001	.001	3	2
UCEC	IGHD2-2 →	+1.726	+2.235	<.001	<.001	3	2
LUSC	RNU6-1090P →	+0.422	+7.924	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,158 associations by consensus.

MTND4LP19 by ZNHIT6 expression — BLCA

Explore this box plot interactively →