ZNHIT6

Across TCGA cell cohorts, ZNHIT6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,068 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNHIT6-associated GO terms across cancer lineages are Maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), Maturation of LSU-rRNA, and Double-strand break repair via nonhomologous end joining. Each is linked with ZNHIT6 in more than 11 cancer types. Because this analysis shows association rather than direction, both ZNHIT6-to-partner and partner-to-ZNHIT6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) grouped by ZNHIT6-low versus ZNHIT6-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNHIT6→partner) and Y-score (partner→ZNHIT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.119	+0.785	.001	.001	3	12
BLOOD_Leukemia	Maturation of LSU-rRNA →	+0.107	+0.529	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via nonhomologous end joining →	+0.066	+0.925	<.001	<.001	3	11
BLOOD_Lymphoma	Ribosomal large subunit biogenesis →	+0.085	+0.684	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Telomeric 3' overhang formation →	+0.119	+0.781	.003	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Centrosome duplication →	+0.101	+0.925	.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,068 associations by consensus.

Maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) by ZNHIT6 expression — URINARY_TRACT

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