ZNHIT6

Across TCGA cell cohorts, ZNHIT6 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNHIT6-associated genes across cancer lineages are GJA8, NUPR2, and GSG1L2. Each is linked with ZNHIT6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNHIT6-to-partner and partner-to-ZNHIT6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GJA8 grouped by ZNHIT6-low versus ZNHIT6-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNHIT6→partner) and Y-score (partner→ZNHIT6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GJA8 →	+0.019	+5.969	<.001	.001	3	1
BLOOD_Leukemia	NUPR2 →	+0.056	+5.539	<.001	.003	3	1
LARGE_INTESTINE	GSG1L2 →	+0.020	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

GJA8 by ZNHIT6 expression — BLOOD_Leukemia

Explore this box plot interactively →