ZNHIT3

Across TCGA patient cohorts, ZNHIT3 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,035 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNHIT3-associated proteins across cancer lineages are LIG3, CCDC43, and XRCC1. Each is linked with ZNHIT3 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNHIT3-to-partner and partner-to-ZNHIT3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNHIT3 versus LIG3 in LSCC, with a Pearson correlation of 0.81.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNHIT3→partner) and Y-score (partner→ZNHIT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LIG3 →	+0.641	+0.734	<.001	<.001	3	7
BRCA	CCDC43 →	+0.412	+0.517	<.001	<.001	3	7
LSCC	XRCC1 →	+0.407	+0.637	<.001	<.001	3	6
LSCC	ZNF830 →	+0.392	+0.636	<.001	<.001	3	6
LSCC	NLE1 →	+0.513	+0.670	<.001	<.001	3	6
LSCC	RRBP1 →	-0.423	-0.489	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,035 associations by consensus.

ZNHIT3 vs LIG3 — LSCC

Explore this scatter interactively →