ZNHIT2

Across TCGA patient cohorts, ZNHIT2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,368 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNHIT2-associated genes across cancer lineages are NDUFS8, TRMT112, and MEN1. Each is linked with ZNHIT2 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNHIT2-to-partner and partner-to-ZNHIT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNHIT2 versus NDUFS8 in BRCA, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNHIT2→partner) and Y-score (partner→ZNHIT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NDUFS8 →	+0.740	+0.219	<.001	.002	2	6
UCEC	TRMT112 →	+0.567	+0.229	.005	.001	3	5
BRCA	MEN1 →	+0.566	+0.313	<.001	<.001	3	4
BRCA	TKFC →	+0.662	+0.258	<.001	<.001	3	4
BRCA	FAU →	+0.497	+0.238	<.001	<.001	3	4
BRCA	ALG8 →	+0.923	+0.362	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,368 associations by consensus.

ZNHIT2 vs NDUFS8 — BRCA

Explore this scatter interactively →