ZNHIT2

Across TCGA cell cohorts, ZNHIT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,506 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNHIT2-associated GO terms across cancer lineages are CAAX-box protein processing, Spliceosomal tri-snRNP complex assembly, and rRNA pseudouridine synthesis. Each is linked with ZNHIT2 in more than 13 cancer types. Because this analysis shows association rather than direction, both ZNHIT2-to-partner and partner-to-ZNHIT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CAAX-box protein processing grouped by ZNHIT2-low versus ZNHIT2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNHIT2→partner) and Y-score (partner→ZNHIT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	CAAX-box protein processing →	+0.187	+1.740	.001	.001	3	14
BLOOD_Lymphoma	Spliceosomal tri-snRNP complex assembly →	+0.083	+1.043	<.001	<.001	3	13
BONE	rRNA pseudouridine synthesis →	+0.164	+1.760	<.001	<.001	3	12
BONE	snRNA transcription by RNA polymerase III →	+0.085	+1.399	<.001	<.001	3	11
LUNG_SCLC	Spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) →	+0.117	+0.921	<.001	.002	3	11
URINARY_TRACT	Enzyme-directed rRNA pseudouridine synthesis →	+0.106	+1.097	.002	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,506 associations by consensus.

CAAX-box protein processing by ZNHIT2 expression — OESOPHAGUS

Explore this box plot interactively →