ZNHIT1

Across TCGA cell cohorts, ZNHIT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,978 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNHIT1-associated GO terms across cancer lineages are Regulation of mitochondrial ATP synthesis coupled proton transport, Mitochondrial respirasome assembly, and Protein localization to chromatin. Each is linked with ZNHIT1 in more than 9 cancer types. Because this analysis shows association rather than direction, both ZNHIT1-to-partner and partner-to-ZNHIT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitochondrial ATP synthesis coupled proton transport grouped by ZNHIT1-low versus ZNHIT1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNHIT1→partner) and Y-score (partner→ZNHIT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of mitochondrial ATP synthesis coupled proton transport →	+0.116	+0.853	<.001	<.001	3	10
OVARY	Mitochondrial respirasome assembly →	+0.130	+0.799	<.001	<.001	3	9
BONE	Protein localization to chromatin →	-0.116	-0.552	.002	.003	3	9
URINARY_TRACT	Regulation of mRNA catabolic process →	-0.059	-0.854	<.001	.003	3	9
SOFT_TISSUE	Long-chain fatty acid metabolic process →	+0.086	+0.767	<.001	<.001	3	9
LARGE_INTESTINE	Heterochromatin organization →	-0.044	-0.519	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,978 associations by consensus.

Regulation of mitochondrial ATP synthesis coupled proton transport by ZNHIT1 expression — PANCREAS

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