ZNFX1

Across TCGA cell cohorts, ZNFX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,909 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ZNFX1-associated GO terms across cancer lineages are Regulation of cytokine-mediated signaling pathway, Positive regulation of cytokine-mediated signaling pathway, and Positive regulation of canonical NF-kappaB signal transduction. Each is linked with ZNFX1 in more than 16 cancer types. Because this analysis shows association rather than direction, both ZNFX1-to-partner and partner-to-ZNFX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cytokine-mediated signaling pathway grouped by ZNFX1-low versus ZNFX1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNFX1→partner) and Y-score (partner→ZNFX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of cytokine-mediated signaling pathway →	+0.081	+1.038	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cytokine-mediated signaling pathway →	+0.107	+0.825	<.001	<.001	3	16
LIVER	Positive regulation of canonical NF-kappaB signal transduction →	+0.076	+0.948	<.001	.001	3	16
SOFT_TISSUE	Negative regulation of immune response →	+0.093	+1.285	<.001	<.001	3	16
KIDNEY	Regulation of viral process →	+0.115	+1.485	.002	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Regulation of response to cytokine stimulus →	+0.079	+1.028	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,909 associations by consensus.

Regulation of cytokine-mediated signaling pathway by ZNFX1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →