ZNFX1

Across TCGA cell cohorts, ZNFX1 mutation is significantly associated with the RNA expression of many other genes, with 89 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNFX1-associated genes across cancer lineages are FCN2, IQCF5, and PRR32. Each is linked with ZNFX1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNFX1-to-partner and partner-to-ZNFX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FCN2 grouped by ZNFX1-low versus ZNFX1-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNFX1→partner) and Y-score (partner→ZNFX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	FCN2 →	+0.033	+5.087	<.001	.004	3	2
UPPER_AERODIGESTIVE_TRACT	IQCF5 →	+0.042	+4.357	<.001	.006	3	2
LUNG_NSCLC_LUSC	PRR32 →	+0.142	+4.584	.004	.001	3	1
URINARY_TRACT	GH2 →	+0.030	+5.087	<.001	.004	3	1
PANCREAS	MYOD1 →	+0.033	+3.786	<.001	.004	3	1
PANCREAS	HCRT →	+0.065	+4.035	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 89 associations by consensus.

FCN2 by ZNFX1 expression — URINARY_TRACT

Explore this box plot interactively →