Across TCGA patient cohorts, ZNF99 mutation is significantly associated with the total protein of many other genes, with 68 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF99-associated genes across cancer lineages are Cyclin-B1, ACC1, and ASNS. Each is linked with ZNF99 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF99-to-partner and partner-to-ZNF99 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF99→partner) and Y-score (partner→ZNF99) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Cyclin-B1 →	+0.670	+1.584	<.001	<.001	3	5
UCEC	ACC1 →	+0.240	+1.099	.015	.016	3	4
UCEC	ASNS →	+0.327	+1.263	<.001	.016	3	4
STAD	RAD51 →	+0.193	+3.000	.039	.033	3	3
BLCA	HSP70 →	-0.407	-2.999	.027	.035	3	3
UCEC	MEK1 →	+0.374	+1.765	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 68 associations by consensus.

Exploration

ZNF99 survival (RNA) · tumor vs normal (RNA) · all ZNF99 data types