Across TCGA cell cohorts, ZNF99 mutation is significantly associated with the RNA expression of many other genes, with 270 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF99-associated genes across cancer lineages are CGB3, RXFP2, and DAZL. Each is linked with ZNF99 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF99-to-partner and partner-to-ZNF99 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF99→partner) and Y-score (partner→ZNF99) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CGB3 →	+0.048	+4.121	<.001	<.001	3	2
BLOOD_Leukemia	RXFP2 →	+0.505	+3.149	.001	.009	3	2
LUNG_SCLC	DAZL →	+0.830	+4.070	.001	.003	3	2
LARGE_INTESTINE	TTC27 →	+0.478	+3.299	.004	.004	3	2
BLOOD_Myeloma	MMP26 →	+0.026	+4.807	<.001	.006	3	1
BLOOD_Leukemia	CSN2 →	+0.011	+3.969	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 270 associations by consensus.

Exploration

ZNF99 survival (RNA) · tumor vs normal (RNA) · all ZNF99 data types