ZNF92

Across TCGA cell cohorts, ZNF92 mutation is significantly associated with the drug of many other genes, with 43 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF92-associated genes across cancer lineages are Veliparib, Mirin, and EHT-1864. Each is linked with ZNF92 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF92-to-partner and partner-to-ZNF92 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Veliparib grouped by ZNF92-low versus ZNF92-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF92→partner) and Y-score (partner→ZNF92) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Veliparib →	+0.396	+2.807	.002	.046	3	1
LARGE_INTESTINE	Mirin →	+0.426	+2.807	.012	.037	3	1
LARGE_INTESTINE	EHT-1864 →	+0.399	+2.678	.012	.037	3	1
LARGE_INTESTINE	5-Fluorouracil →	+0.599	+3.184	.022	.007	3	1
LARGE_INTESTINE	Gemcitabine →	+0.832	+2.807	.030	.046	3	1
LARGE_INTESTINE	LCL161 →	+0.348	+3.061	.018	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

Veliparib by ZNF92 expression — LARGE_INTESTINE

Explore this box plot interactively →