ZNF91

Across TCGA patient cohorts, ZNF91 mutation is significantly associated with the RNA expression of many other genes, with 4,104 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF91-associated genes across cancer lineages are CICP12, HAUS1, and HPGDS. Each is linked with ZNF91 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF91-to-partner and partner-to-ZNF91 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CICP12 grouped by ZNF91-low versus ZNF91-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF91→partner) and Y-score (partner→ZNF91) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	CICP12 →	+0.098	+3.990	.001	.002	3	4
UCEC	HAUS1 →	+0.476	+1.501	<.001	<.001	3	3
UCEC	HPGDS →	-0.325	-1.458	<.001	<.001	3	3
UCEC	UQCRH →	+0.566	+1.906	.005	.001	3	3
UCEC	TRO →	-0.686	-1.458	.003	<.001	3	3
UCEC	CDC7 →	+0.565	+2.178	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,104 associations by consensus.

CICP12 by ZNF91 expression — LIHC

Explore this box plot interactively →