ZNF91

Across TCGA cell cohorts, ZNF91 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,657 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF91-associated GO terms across cancer lineages are Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway, Copper ion export, and Transposable element silencing. Each is linked with ZNF91 in more than 9 cancer types. Because this analysis shows association rather than direction, both ZNF91-to-partner and partner-to-ZNF91 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway grouped by ZNF91-low versus ZNF91-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF91→partner) and Y-score (partner→ZNF91) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	+0.123	+1.885	.002	.001	3	10
BLOOD_Leukemia	Copper ion export →	-0.138	-0.975	<.001	<.001	3	9
BLOOD_Leukemia	Transposable element silencing →	+0.074	+0.973	<.001	.002	3	9
LUNG_SCLC	Regulation of DNA-templated transcription initiation →	+0.061	+0.911	<.001	<.001	3	9
SOFT_TISSUE	Regulation of cytoplasmic translation →	+0.079	+1.118	<.001	.001	3	8
LUNG_SCLC	Regulation of transcription initiation by RNA polymerase II →	+0.059	+1.046	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,657 associations by consensus.

Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway by ZNF91 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →