ZNF91

Across TCGA cell cohorts, ZNF91 mutation is significantly associated with the RNA expression of many other genes, with 217 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF91-associated genes across cancer lineages are SHCBP1L, TMPRSS7, and CLDN34. Each is linked with ZNF91 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF91-to-partner and partner-to-ZNF91 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SHCBP1L grouped by ZNF91-low versus ZNF91-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF91→partner) and Y-score (partner→ZNF91) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	SHCBP1L →	+0.701	+3.628	.001	.002	3	2
BLOOD_Leukemia	TMPRSS7 →	+0.036	+3.106	<.001	.005	3	2
BLOOD_Leukemia	CLDN34 →	+0.038	+4.247	<.001	.004	3	2
LARGE_INTESTINE	GPR63 →	+0.568	+2.043	.005	.008	3	2
LARGE_INTESTINE	MUC2 →	+1.802	+2.043	.001	.008	3	2
BLOOD_Myeloma	MYL7 →	+0.045	+3.321	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 217 associations by consensus.

SHCBP1L by ZNF91 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →