Across TCGA pan-cancer cohorts, ZNF90P2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of ZNF90P2’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ZNF90P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ZNF90P2 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.
KIRC and LUSC are the cancer types where ZNF90P2 tumor–normal differential expression is most reproducible.