Across TCGA patient cohorts, ZNF888 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,899 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ZNF888-associated proteins across cancer lineages are SHROOM3_S1173, B4GALT4, and TJP3. Each is linked with ZNF888 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF888-to-partner and partner-to-ZNF888 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF888→partner) and Y-score (partner→ZNF888) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SHROOM3_S1173 →	+0.845	+0.429	.002	.001	3	4
UCEC	B4GALT4 →	+0.400	+0.591	.001	.005	3	4
UCEC	TJP3 →	+0.509	+0.857	<.001	<.001	3	4
LUAD	TJP3_S203 →	+0.588	+0.466	<.001	<.001	3	4
BRCA	TJP3_S591 →	+0.741	+0.506	.001	.002	3	4
UCEC	TRPM4 →	+0.601	+0.718	.002	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,899 associations by consensus.

Exploration

ZNF888 survival (RNA) · tumor vs normal (RNA) · all ZNF888 data types