Across TCGA patient cohorts, ZNF888 protein abundance is significantly associated with the RNA expression of many other genes, with 363 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF888-associated genes across cancer lineages are SERPINI1, DEFA4, and INPPL1. Each is linked with ZNF888 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF888-to-partner and partner-to-ZNF888 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF888→partner) and Y-score (partner→ZNF888) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SERPINI1 →	-0.815	-0.364	.004	.005	3	1
LUAD	DEFA4 →	+0.229	+0.461	<.001	.007	3	1
LUAD	INPPL1 →	-0.505	-0.376	<.001	.003	3	1
LUAD	OR6T1 →	+0.192	+0.421	<.001	.004	3	1
LUAD	PSORS1C1 →	-0.782	-0.275	<.001	.002	3	1
LUAD	PLPP6 →	-0.559	-0.376	.006	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 363 associations by consensus.

Exploration

ZNF888 survival (RNA) · tumor vs normal (RNA) · all ZNF888 data types