Across TCGA pan-cancer cohorts, ZNF885P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of ZNF885P’s most consistent transcriptional readouts.
The strongest signal is observed in kidney chromophobe (KICH), where ZNF885P RNA is repressed in tumor relative to normal tissue. In most cancer types ZNF885P is over-expressed in tumor, although a few such as KICH and KIRP show the opposite, repressed pattern.
KICH, KIRC, and KIRP are the cancer types where ZNF885P tumor–normal differential expression is most reproducible.