Across TCGA patient cohorts, ZNF880 mutation is significantly associated with the RNA expression of many other genes, with 3,036 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF880-associated genes across cancer lineages are UBE2L2, LYPLA1P1, and MBD3L3. Each is linked with ZNF880 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF880-to-partner and partner-to-ZNF880 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF880→partner) and Y-score (partner→ZNF880) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	UBE2L2 →	+0.139	+4.234	<.001	.008	3	3
COAD	LYPLA1P1 →	+0.211	+4.824	<.001	.002	3	3
HNSC	MBD3L3 →	+0.272	+5.736	<.001	.003	3	2
CESC	ANOS2P →	+0.018	+4.539	<.001	.008	3	2
CESC	BNIP3P7 →	+0.091	+6.584	<.001	<.001	3	2
COAD	RN7SL804P →	+0.376	+3.956	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,036 associations by consensus.

Exploration

ZNF880 survival (RNA) · tumor vs normal (RNA) · all ZNF880 data types