ZNF880

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF880 mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF880-associated genes across cancer lineages are 14-3-3_beta, mTOR_pS2448, and PDCD4. Each is linked with ZNF880 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF880-to-partner and partner-to-ZNF880 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF880→partner) and Y-score (partner→ZNF880) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCEC14-3-3_beta →-0.077-2.295.040.03332
UCECmTOR_pS2448 →-0.136-2.095.015.01732
UCECPDCD4 →-0.640-3.584<.001.00232
UCECShc_pY317 →-0.216-3.584<.001.00232
UCECSTAT3_pY705 →-0.489-2.415<.001.00232
UCECASNS →+0.542+3.584<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

Exploration