Across TCGA cell cohorts, ZNF880 mutation is significantly associated with the drug of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF880-associated genes across cancer lineages are GSK2801, GSK2256098C, and GSK626616AC. Each is linked with ZNF880 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF880-to-partner and partner-to-ZNF880 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF880→partner) and Y-score (partner→ZNF880) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GSK2801 →	+0.432	+2.871	.003	.021	3	1
LARGE_INTESTINE	GSK2256098C →	+0.309	+3.129	.034	.014	3	1
LARGE_INTESTINE	GSK626616AC →	+0.320	+3.000	.035	.017	3	1
LARGE_INTESTINE	FTY-720 →	+0.204	+2.700	.036	.047	3	1
LARGE_INTESTINE	Kobe2602 →	+0.283	+2.807	.021	.044	3	1
LARGE_INTESTINE	JAK3_7406 →	+0.495	+2.871	.010	.021	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

ZNF880 survival (RNA) · tumor vs normal (RNA) · all ZNF880 data types