ZNF875

Across TCGA patient cohorts, ZNF875 mutation is significantly associated with the RNA expression of many other genes, with 4,776 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF875-associated genes across cancer lineages are CCDC163, ATP6V1G1P3, and SRSF6P1. Each is linked with ZNF875 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF875-to-partner and partner-to-ZNF875 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC163 grouped by ZNF875-low versus ZNF875-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF875→partner) and Y-score (partner→ZNF875) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCDC163 →	+0.534	+2.922	<.001	<.001	3	3
UCEC	ATP6V1G1P3 →	+0.078	+2.105	.001	.008	3	3
CESC	SRSF6P1 →	+0.072	+5.969	<.001	.002	3	2
CESC	NMD3P2 →	+0.057	+5.010	<.001	.009	3	2
UCEC	KRT18P9 →	+0.132	+1.701	.006	.005	3	2
UCEC	TAF9 →	+0.673	+3.459	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,776 associations by consensus.

CCDC163 by ZNF875 expression — UCEC

Explore this box plot interactively →