ZNF865

Across TCGA cell cohorts, ZNF865 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,258 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ZNF865-associated GO terms across cancer lineages are Positive regulation of cellular response to transforming growth factor beta stimulus, Positive regulation of transforming growth factor beta receptor signaling pathway, and Positive regulation of intracellular steroid hormone receptor signaling pathway. Each is linked with ZNF865 in more than 15 cancer types. Because this analysis shows association rather than direction, both ZNF865-to-partner and partner-to-ZNF865 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cellular response to transforming growth factor beta stimulus grouped by ZNF865-low versus ZNF865-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF865→partner) and Y-score (partner→ZNF865) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Positive regulation of cellular response to transforming growth factor beta stimulus →	+0.139	+1.001	<.001	<.001	3	16
KIDNEY	Positive regulation of transforming growth factor beta receptor signaling pathway →	+0.139	+1.001	<.001	<.001	3	16
OESOPHAGUS	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.190	+1.016	<.001	.002	3	16
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.179	+0.977	<.001	<.001	3	15
CNS	Negative regulation of calcium ion export across plasma membrane →	+0.082	+0.863	<.001	<.001	3	15
LUNG_SCLC	Regulation of protein sumoylation →	+0.119	+0.992	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,258 associations by consensus.

Positive regulation of cellular response to transforming growth factor beta stimulus by ZNF865 expression — KIDNEY

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