ZNF862

Across TCGA patient cohorts, ZNF862 mutation is significantly associated with the RNA expression of many other genes, with 6,846 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF862-associated genes across cancer lineages are FCER1A, KIF9, and VRK1. Each is linked with ZNF862 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF862-to-partner and partner-to-ZNF862 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FCER1A grouped by ZNF862-low versus ZNF862-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF862→partner) and Y-score (partner→ZNF862) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FCER1A →	-0.771	-1.862	<.001	<.001	3	4
SKCM	KIF9 →	+0.392	+3.739	.001	<.001	3	4
UCEC	VRK1 →	+0.415	+2.673	.002	<.001	3	4
UCEC	GINS2 →	+1.048	+2.469	<.001	<.001	3	4
UCEC	CEP55 →	+0.511	+1.263	.001	.002	3	4
UCEC	GINS4 →	+0.540	+2.102	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,846 associations by consensus.

FCER1A by ZNF862 expression — UCEC

Explore this box plot interactively →