ZNF862

Across TCGA patient cohorts, ZNF862 mutation is significantly associated with the total protein of many other genes, with 79 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF862-associated genes across cancer lineages are eEF2, TFRC, and TIGAR. Each is linked with ZNF862 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF862-to-partner and partner-to-ZNF862 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by ZNF862-low versus ZNF862-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF862→partner) and Y-score (partner→ZNF862) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.282	+1.847	.003	.007	3	3
UCEC	TFRC →	+0.473	+3.087	<.001	<.001	3	3
UCEC	TIGAR →	+0.097	+1.026	.018	.017	3	3
UCEC	ATM →	-0.568	-1.807	<.001	<.001	3	3
UCEC	4E-BP1 →	+0.278	+3.247	<.001	<.001	3	3
SKCM	SCD →	-0.137	-2.115	.030	.018	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 79 associations by consensus.

eEF2 by ZNF862 expression — UCEC

Explore this box plot interactively →