Across TCGA pan-cancer cohorts, ZNF861P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of ZNF861P’s most consistent transcriptional readouts.
The strongest signal is observed in bladder urothelial carcinoma (BLCA), where ZNF861P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ZNF861P is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
BLCA, THCA, and READ are the cancer types where ZNF861P tumor–normal differential expression is most reproducible.