Across TCGA pan-cancer cohorts, ZNF860 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ZNF860 data layer compared with 22 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher ZNF860 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF860 expression acts as an unfavorable survival marker.

HNSC, OV, and LIHC are the cancer types where ZNF860 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.138	0.710	.001	24	view →
OV	DFS	Median	All	0.142	0.541	.002	12	view →
LIHC	DFS	Median	All	0.091	0.543	.012	9	view →
LUSC	OS	Median	All	0.011	0.819	<.001	6	view →
ACC	DFS	Median	All	0.195	0.748	.003	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: ZNF860 tumor-vs-normal RNA expression · all ZNF860 data types