Across TCGA patient cohorts, ZNF860 mutation is significantly associated with the RNA expression of many other genes, with 1,446 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF860-associated genes across cancer lineages are ADAM33, TRMT44, and CCNB2. Each is linked with ZNF860 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF860-to-partner and partner-to-ZNF860 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF860→partner) and Y-score (partner→ZNF860) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ADAM33 →	-0.681	-2.898	.008	.001	3	2
UCEC	TRMT44 →	+0.259	+1.748	.003	.002	3	2
UCEC	CCNB2 →	+0.572	+2.930	.003	<.001	3	2
UCEC	PANK4 →	+0.328	+2.010	.002	<.001	3	2
UCEC	DONSON →	+0.370	+1.773	.007	.008	3	2
UCEC	PEF1 →	+0.280	+3.786	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,446 associations by consensus.

Exploration

ZNF860 survival (RNA) · tumor vs normal (RNA) · all ZNF860 data types