Across TCGA patient cohorts, ZNF860 mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. COAD shows the largest number of these associations.

The most reproducible ZNF860-associated genes across cancer lineages are eIF4E, PDCD4, and HER3. Each is linked with ZNF860 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF860-to-partner and partner-to-ZNF860 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF860→partner) and Y-score (partner→ZNF860) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	eIF4E →	+0.259	+2.820	.005	.035	3	2
COAD	PDCD4 →	-0.449	-2.991	.040	.036	3	2
UCEC	HER3 →	+0.264	+1.375	.006	.024	3	1
UCEC	MEK1 →	+0.410	+2.502	.001	.001	3	1
UCEC	p62 Lck ligand →	+0.369	+2.817	.001	.001	3	1
UCEC	p90 RSK →	+0.146	+1.375	.031	.024	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

ZNF860 survival (RNA) · tumor vs normal (RNA) · all ZNF860 data types