ZNF853

Across TCGA patient cohorts, ZNF853 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,627 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF853-associated proteins across cancer lineages are HDGFL3, LYN, and SEPTIN7. Each is linked with ZNF853 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF853-to-partner and partner-to-ZNF853 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF853 versus HDGFL3 in BRCA, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF853→partner) and Y-score (partner→ZNF853) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HDGFL3 →	+0.572	+0.734	.002	.001	3	7
LSCC	LYN →	-0.541	-1.266	<.001	<.001	3	6
PDAC	SEPTIN7 →	+0.264	+0.423	<.001	<.001	3	6
CCRCC	ARHGEF17 →	+0.321	+0.470	<.001	<.001	3	6
OV	PSME2 →	-0.507	-1.085	<.001	<.001	3	6
HNSC	MAP1A_S667 →	+0.787	+0.657	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,627 associations by consensus.

ZNF853 vs HDGFL3 — BRCA

Explore this scatter interactively →