ZNF853

Across TCGA patient cohorts, ZNF853 protein abundance is significantly associated with the RNA expression of many other genes, with 4,369 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF853-associated genes across cancer lineages are BCHE, HSPB7, and SLC24A3-AS1. Each is linked with ZNF853 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF853-to-partner and partner-to-ZNF853 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF853 versus BCHE in UCEC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF853→partner) and Y-score (partner→ZNF853) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BCHE →	+1.567	+0.600	<.001	<.001	3	3
UCEC	HSPB7 →	+1.016	+0.442	<.001	.004	3	3
GBM	SLC24A3-AS1 →	+1.402	+0.817	<.001	<.001	3	3
GBM	SLC24A3 →	+1.456	+0.814	<.001	<.001	3	3
LSCC	PARD3B →	+0.596	+0.439	.005	<.001	3	2
LUAD	F10 →	+0.977	+0.572	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,369 associations by consensus.

ZNF853 vs BCHE — UCEC

Explore this scatter interactively →