ZNF853

Across TCGA cell cohorts, ZNF853 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,808 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ZNF853-associated GO terms across cancer lineages are RNA splicing, via transesterification reactions, RNA splicing, via transesterification reactions with bulged adenosine as nucleophile, and mRNA splicing, via spliceosome. Each is linked with ZNF853 in more than 14 cancer types. Because this analysis shows association rather than direction, both ZNF853-to-partner and partner-to-ZNF853 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA splicing, via transesterification reactions grouped by ZNF853-low versus ZNF853-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF853→partner) and Y-score (partner→ZNF853) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	RNA splicing, via transesterification reactions →	+0.071	+1.128	<.001	<.001	3	15
SOFT_TISSUE	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.071	+1.111	<.001	<.001	3	15
SOFT_TISSUE	mRNA splicing, via spliceosome →	+0.071	+1.111	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Transcription initiation at RNA polymerase II promoter →	+0.084	+0.817	<.001	.002	3	14
URINARY_TRACT	Regulation of RNA splicing →	+0.052	+1.308	.007	.001	3	14
STOMACH	Negative regulation of mRNA metabolic process →	+0.070	+1.101	<.001	.004	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,808 associations by consensus.

RNA splicing, via transesterification reactions by ZNF853 expression — SOFT_TISSUE

Explore this box plot interactively →