ZNF852

Across TCGA patient cohorts, ZNF852 mutation is significantly associated with the RNA expression of many other genes, with 3,877 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF852-associated genes across cancer lineages are RNU7-9P, AKR1B1P3, and SNORD116-10. Each is linked with ZNF852 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF852-to-partner and partner-to-ZNF852 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU7-9P grouped by ZNF852-low versus ZNF852-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF852→partner) and Y-score (partner→ZNF852) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU7-9P →	+0.568	+7.924	<.001	.008	3	2
UCEC	AKR1B1P3 →	+0.180	+1.759	.002	.002	3	2
SKCM	SNORD116-10 →	+0.216	+4.302	<.001	.007	3	2
SKCM	RNU6-660P →	+0.551	+5.054	<.001	<.001	3	2
UCEC	MIR4701 →	+0.609	+1.878	<.001	.001	3	2
COAD	POLR3KP2 →	+0.255	+4.418	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,877 associations by consensus.

RNU7-9P by ZNF852 expression — LUSC

Explore this box plot interactively →