ZNF850

Across TCGA patient cohorts, ZNF850 mutation is significantly associated with the RNA expression of many other genes, with 3,413 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF850-associated genes across cancer lineages are MIR7973-1, VTRNA2-2P, and RNA5SP34. Each is linked with ZNF850 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF850-to-partner and partner-to-ZNF850 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR7973-1 grouped by ZNF850-low versus ZNF850-high in SARC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF850→partner) and Y-score (partner→ZNF850) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SARC	MIR7973-1 →	+0.388	+5.064	<.001	.002	3	2
CESC	VTRNA2-2P →	+0.376	+4.601	<.001	.004	3	2
LUSC	RNA5SP34 →	+0.261	+7.924	<.001	.008	3	2
CESC	MIR7-3 →	+0.275	+5.342	<.001	.002	3	2
UCEC	IGLV5-45 →	+1.006	+1.540	.004	.001	3	2
UCEC	IGHV6-1 →	+0.570	+1.329	.002	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,413 associations by consensus.

MIR7973-1 by ZNF850 expression — SARC

Explore this box plot interactively →