ZNF850

Across TCGA cell cohorts, ZNF850 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,966 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZNF850-associated GO terms across cancer lineages are Spindle assembly, Microtubule organizing center organization, and Regulation of sister chromatid segregation. Each is linked with ZNF850 in more than 12 cancer types. Because this analysis shows association rather than direction, both ZNF850-to-partner and partner-to-ZNF850 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spindle assembly grouped by ZNF850-low versus ZNF850-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF850→partner) and Y-score (partner→ZNF850) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Spindle assembly →	+0.079	+0.736	.001	<.001	3	13
BONE	Microtubule organizing center organization →	+0.081	+1.251	<.001	<.001	3	13
BREAST	Regulation of sister chromatid segregation →	+0.100	+1.037	<.001	<.001	3	13
BLOOD_Lymphoma	Regulation of mitotic sister chromatid segregation →	+0.111	+1.097	<.001	<.001	3	13
BREAST	Regulation of chromosome segregation →	+0.116	+1.220	<.001	<.001	3	13
BONE	Regulation of chromosome condensation →	+0.181	+0.811	.002	.005	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,966 associations by consensus.

Spindle assembly by ZNF850 expression — BLOOD_Myeloma

Explore this box plot interactively →