ZNF850

Across TCGA cell cohorts, ZNF850 mutation is significantly associated with the RNA expression of many other genes, with 458 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF850-associated genes across cancer lineages are OR2T12, RWDD2A, and FRA10AC1. Each is linked with ZNF850 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF850-to-partner and partner-to-ZNF850 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2T12 grouped by ZNF850-low versus ZNF850-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF850→partner) and Y-score (partner→ZNF850) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	OR2T12 →	+0.007	+4.058	<.001	.009	3	2
LARGE_INTESTINE	RWDD2A →	+0.497	+3.169	<.001	.009	3	2
LARGE_INTESTINE	FRA10AC1 →	+0.559	+3.321	.001	.003	3	2
LARGE_INTESTINE	PGAP2 →	+0.466	+3.743	.004	<.001	3	2
OESOPHAGUS	SLC35G4 →	+0.020	+4.906	<.001	.006	3	1
OESOPHAGUS	LY6L →	+0.020	+4.906	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 458 associations by consensus.

OR2T12 by ZNF850 expression — BLOOD_Lymphoma

Explore this box plot interactively →