ZNF846

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF846 mutation is significantly associated with the total protein of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF846-associated genes across cancer lineages are C-Raf, eEF2, and FoxM1. Each is linked with ZNF846 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF846-to-partner and partner-to-ZNF846 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF846→partner) and Y-score (partner→ZNF846) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECC-Raf →+0.233+3.700<.001.00133
UCECeEF2 →+0.397+1.700.008.04432
UCECFoxM1 →+0.227+1.700.039.04432
UCECFOXO3a_pS318_S321 →-0.166-2.690.001.00632
UCECJNK_pT183_Y185 →-0.237-2.209<.001.01132
UCECKu80 →+0.279+2.235.005.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

Exploration