Across TCGA cell cohorts, ZNF846 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF846-associated genes across cancer lineages are SLC7A13, SPATA8, and IFNA10. Each is linked with ZNF846 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF846-to-partner and partner-to-ZNF846 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF846→partner) and Y-score (partner→ZNF846) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	SLC7A13 →	+0.006	+6.247	<.001	<.001	3	1
BLOOD_Lymphoma	SPATA8 →	+0.176	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	IFNA10 →	+0.042	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	TSPY3 →	+0.034	+5.209	<.001	.005	3	1
LARGE_INTESTINE	SLCO1C1 →	+0.534	+3.620	<.001	.003	3	1
LARGE_INTESTINE	MMP26 →	+0.033	+3.217	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

ZNF846 survival (RNA) · tumor vs normal (RNA) · all ZNF846 data types