ZNF845

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF845 mutation is significantly associated with the total protein of many other genes, with 59 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF845-associated genes across cancer lineages are Shc_pY317, ATM, and p53. Each is linked with ZNF845 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF845-to-partner and partner-to-ZNF845 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF845→partner) and Y-score (partner→ZNF845) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMShc_pY317 →-0.223-2.304.018.03533
UCECATM →-0.559-2.571<.001<.00133
SKCMp53 →-0.189-2.304.043.03532
UCEC14-3-3_beta →-0.084-2.388.004.00232
UCECEGFR_pY1068 →-0.280-2.369<.001<.00132
UCECeIF4E →+0.193+2.099.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

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