Across TCGA cell cohorts, ZNF845 mutation is significantly associated with the mutation status of many other genes, with 3,649 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF845-associated genes across cancer lineages are HELZ2, IQSEC1, and TCF7L2. Each is linked with ZNF845 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF845-to-partner and partner-to-ZNF845 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF845→partner) and Y-score (partner→ZNF845) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	HELZ2 →	+2.847	+4.327	.006	.006	1	4
SOFT_TISSUE	IQSEC1 →	+4.502	+5.066	.007	.007	1	4
SOFT_TISSUE	TCF7L2 →	+5.502	+5.502	.003	.003	1	4
SOFT_TISSUE	ENTHD1 →	+5.502	+5.502	.003	.003	1	4
CNS	C3 →	+4.044	+5.000	.008	.008	1	4
LARGE_INTESTINE	CNTN4 →	+1.854	+2.702	.002	.002	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,649 associations by consensus.

Exploration

ZNF845 survival (RNA) · tumor vs normal (RNA) · all ZNF845 data types