Across TCGA pan-cancer cohorts, ZNF844 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ZNF844 data layer compared with 20 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher ZNF844 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF844 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

ESCA, SKCM, and UCEC are the cancer types where ZNF844 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	II,III,IV	0.248	0.686	.019	9	view →
SKCM	OS	Median	II,III,IV	0.320	0.735	.015	8	view →
UCEC	DFS	Median	II,III,IV	0.877	0.435	.035	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: ZNF844 tumor-vs-normal RNA expression · all ZNF844 data types