ZNF843

Across TCGA pan-cancer cohorts, ZNF843 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ZNF843 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher ZNF843 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF843 expression acts as an unfavorable survival marker.

ESCA, LIHC, and UCEC are the cancer types where ZNF843 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Median	All	0.210	0.704	.001	24	view →
LIHC	DFS	Median	II,III,IV	0.044	0.427	<.001	8	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ZNF843–ESCA (OS)

Open the ESCA breakdown →