ZNF839

Across TCGA cell cohorts, ZNF839 mutation is significantly associated with the RNA expression of many other genes, with 317 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF839-associated genes across cancer lineages are RNF216, TENT4A, and CEP290. Each is linked with ZNF839 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF839-to-partner and partner-to-ZNF839 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNF216 grouped by ZNF839-low versus ZNF839-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF839→partner) and Y-score (partner→ZNF839) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RNF216 →	+0.663	+3.169	.001	.009	3	2
LARGE_INTESTINE	TENT4A →	+0.734	+3.364	.003	.002	3	2
LARGE_INTESTINE	CEP290 →	+0.688	+3.067	<.001	.009	3	2
BREAST	REG1B →	+1.039	+5.169	<.001	.005	3	2
SOFT_TISSUE	KRTAP5-11 →	+0.022	+4.977	<.001	.002	3	1
SOFT_TISSUE	KRTAP29-1 →	+0.017	+4.369	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 317 associations by consensus.

RNF216 by ZNF839 expression — LARGE_INTESTINE

Explore this box plot interactively →