ZNF837

Across TCGA patient cohorts, ZNF837 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,162 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZNF837-associated GO terms across cancer lineages are Positive regulation of sphingolipid biosynthetic process, Motile cilium assembly, and tRNA thio-modification. Each is linked with ZNF837 in more than 22 cancer types. Because this analysis shows association rather than direction, both ZNF837-to-partner and partner-to-ZNF837 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of sphingolipid biosynthetic process grouped by ZNF837-low versus ZNF837-high in PAAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF837→partner) and Y-score (partner→ZNF837) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PAAD	Positive regulation of sphingolipid biosynthetic process →	+0.061	+0.638	<.001	<.001	3	23
KIRP	Motile cilium assembly →	+0.032	+0.473	<.001	<.001	3	22
READ	tRNA thio-modification →	+0.076	+0.876	<.001	<.001	3	22
PAAD	Regulation of cytochrome-c oxidase activity →	+0.047	+0.568	<.001	<.001	3	20
GBM	Axoneme assembly →	+0.043	+0.546	<.001	<.001	2	21
GBM	Sperm flagellum assembly →	+0.030	+0.459	<.001	<.001	2	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,162 associations by consensus.

Positive regulation of sphingolipid biosynthetic process by ZNF837 expression — PAAD

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