ZNF837

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF837 protein abundance is significantly associated with the RNA expression of many other genes, with 834 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF837-associated genes across cancer lineages are ASTN2, ATRNL1, and PSMB2. Each is linked with ZNF837 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF837-to-partner and partner-to-ZNF837 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF837 versus ASTN2 in LSCC, with a Pearson correlation of -0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF837→partner) and Y-score (partner→ZNF837) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCASTN2 →-2.228-0.527<.001<.00132
BRCAATRNL1 →+1.456+0.604.002.00531
BRCAPSMB2 →-0.384-0.558.004.00131
BRCAMTG1 →+0.747+0.595.002.00231
BRCATEPSIN →+0.671+0.704.006.00531
BRCAHEXD →+0.780+0.672.006.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 834 associations by consensus.

ZNF837 vs ASTN2 — LSCC

Per-sample scatter of ZNF837 vs ASTN2 in LSCC (Pearson r = -0.60).

Explore this scatter interactively →

Exploration