ZNF837

Across TCGA patient cohorts, ZNF837 mutation is significantly associated with the RNA expression of many other genes, with 107 significant associations in total. COAD shows the largest number of these associations.

The most reproducible ZNF837-associated genes across cancer lineages are RNA5SP421, RNU6-275P, and RNA5SP414. Each is linked with ZNF837 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF837-to-partner and partner-to-ZNF837 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP421 grouped by ZNF837-low versus ZNF837-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF837→partner) and Y-score (partner→ZNF837) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP421 →	+1.096	+3.925	<.001	<.001	3	2
COAD	RNU6-275P →	+0.155	+4.927	<.001	.002	3	2
UCEC	RNA5SP414 →	+1.142	+4.577	<.001	<.001	3	1
UCEC	RNA5SP411 →	+1.877	+3.715	<.001	.001	3	1
UCEC	RNA5SP412 →	+0.679	+3.382	.007	.004	3	1
BRCA	RNU6-839P →	+0.274	+8.471	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 107 associations by consensus.

RNA5SP421 by ZNF837 expression — UCEC

Explore this box plot interactively →