ZNF837

Across TCGA cell cohorts, ZNF837 mutation is significantly associated with the RNA expression of many other genes, with 41 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF837-associated genes across cancer lineages are EPPIN, GLRA2, and PHOX2B. Each is linked with ZNF837 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF837-to-partner and partner-to-ZNF837 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EPPIN grouped by ZNF837-low versus ZNF837-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF837→partner) and Y-score (partner→ZNF837) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	EPPIN →	+0.006	+3.507	<.001	.004	3	2
BLOOD_Leukemia	GLRA2 →	+0.025	+4.376	<.001	<.001	3	1
BLOOD_Leukemia	PHOX2B →	+0.013	+3.365	.006	.005	3	1
BLOOD_Leukemia	TP53AIP1 →	+0.069	+3.554	.003	.007	3	1
BLOOD_Leukemia	GSC →	+0.724	+2.948	.006	.008	3	1
BLOOD_Leukemia	HRK →	+1.068	+3.321	.006	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

EPPIN by ZNF837 expression — BLOOD_Leukemia

Explore this box plot interactively →