ZNF83

Across TCGA pan-cancer cohorts, ZNF83 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ZNF83 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ZNF83 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF83 expression acts as an unfavorable survival marker.

KIRC, BLCA, and READ are the cancer types where ZNF83 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.133	0.796	<.001	42	view →
BLCA	DFS	Median	All	0.226	0.627	.026	12	view →
READ	OS	Median	II,III,IV	0.527	0.933	<.001	9	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
LUAD	DFS	Median	All	0.352	0.678	.043	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ZNF83–KIRC (DFS)

Open the KIRC breakdown →